Lallemand Animal Nutrition
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What's new

Dec 01, 2016

New research on the potential of specific yeast fraction in food safety

Dec 01, 2016

During the latest Symposium on Gut Health in Production of Food Animals, November 14-16 2016, in Saint Louis, Missouri, Lysiane Dunière, Research scientist at Lallemand Animal Nutrition Ruminant Center of Excellence (Clermont-Ferrand, France), presented a poster on yeast cell fraction potential in food safety1.

Laurent Dussert explains: “Farm animals can represent a reservoir of potential pathogens for consumers, such as certain E. coli strains. At a time of increased pressure to reduce the use of antibiotics in animal feed, every effort should be made to limit pathogens introduction in the food chain from animal production with sustainable, natural solutions. Yeast fractions, in particular yeast cell walls, are well-described for their pathogen-binding ability, facilitating their clearance from the gut lumen and limiting their development. Scientists at Lallemand Animal Nutrition have developed a new method to screen yeast derivatives according to their binding ability thanks to a better understanding of yeast structure-function relationship. “

Lysiane Dunière summarizes the study: “One of the yeast fractions selected in our lab was tested in vitro for its ability to prevent the adhesion of Enteropathogenic E. coli (EPEC) strain to intestinal cells. The yeast fraction tested effectively prevented the adhesion of the bacteria to the epithelial cells, but also promoted bacteria dislodgment when the yeast cell wall was added post-infection. The results are promising and in-line with other results with this yeast product on other pathogens. Today, we can conclude on the potential of this particular yeast product in vitro while further in vivo studies will be required to confirm its potential to limit pathogen adhesion in animal gut.”


1 Lysiane Dunière, Cécile Verdier, Frédérique Chaucheyras-Durand, Mathieu Castex. Yeast cell fractions inhibit EPEC adhesion onto T84 intestinal epithelial cells. Symposium on Gut Health in Production of Food Animals, November 14-16 2016, Saint Louis, Missouri